Whelan lab

Ó Faoláin Lab

Centre for Immunobiology and Infection

Blizard Institute

Queen Mary University London


Understanding how pathogens and disease hijack nucleocytoplasmic trafficking and the nuclear periphery to alter cell fate.

HIV-1 Nuclear Pore Complex

Understanding how pathogens and disease hijack nucleocytoplasmic trafficking and the nuclear periphery to alter cell fate.

Remodelling of the nuclear pore complex during HIV-1 infection

Remodelling of the Nuclear Envelope during Viral Synapse formation in T cells

Primary T cell nuclear import and export dynamics

Developing and applying live-cell, super-resolution microscopy approaches and advanced image analysis. Transforming images into numbers to uncover manipulation of the host during infection

B

A

Current funding

Wellcome Early Career Award

Future Work

Other Viruses (EBV)

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Genetic Disease (Progeria, RD)

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Immune Synapses

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Other Viruses (EBV) - Genetic Disease (Progeria, RD) - Immune Synapses -

Regulation of the Nuclear Pore Complex and nucleocytoplasmic trafficking underpins all cell biology processes.

Understanding and manipulating their dynamics can inform all infection research and beyond